710
Anti- SQLE Antibody | FNab08209
- SKU:
- 710-FNab08209-GEN
- Availability:
- In Stock - Delivery within a week
Description
Anti- SQLE Antibody | FNab08209 | Gentaur UK, US & Europe Distribution
Form: liquid
Purification: Immunogen affinity purified
Purity: ≥95% as determined by SDS-PAGE
Host: Rabbit
Clonality: polyclonal
Clone ID: N/A
Isotype: IgG
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background: SQLE, also named as ERG1, SE and SM, belongs to the squalene monooxygenase family. It catalyzes the first oxygenation step in cholesterol synthesis, acting on squalene before cyclization into the basic steroid structure. SQLE may serve as a flux-controlling enzyme beyond 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGR, considered as rate limiting) . It is also posttranslationally regulated by cholesterol-dependent proteasomal degradation. (PMID:21356516) The MW of SQLE is about 64kd.
Immunogen: squalene epoxidase
synonyms: ERG1, FLJ30795, SE, SM, SQLE, squalene epoxidase, Squalene monooxygenase
Molecular weight (observed) : 64 kDa
Reactivity Species: Human, Mouse, Rat
Tested Application: ELISA, WB, IHC
Recomended Dillution : WB: 1:200-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200
Research Area: Metabolism