Anti- SQLE Antibody | FNab08209

Anti- SQLE Antibody | FNab08209 | Gentaur UK, US & Europe Distribution

Form: liquid

Purification: Immunogen affinity purified

Purity: ≥95% as determined by SDS-PAGE

Host: Rabbit

Clonality: polyclonal

Clone ID: N/A

Isotype: IgG

Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background: SQLE, also named as ERG1, SE and SM, belongs to the squalene monooxygenase family. It catalyzes the first oxygenation step in cholesterol synthesis, acting on squalene before cyclization into the basic steroid structure. SQLE may serve as a flux-controlling enzyme beyond 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGR, considered as rate limiting) . It is also posttranslationally regulated by cholesterol-dependent proteasomal degradation. (PMID:21356516) The MW of SQLE is about 64kd.

Immunogen: squalene epoxidase

synonyms: ERG1, FLJ30795, SE, SM, SQLE, squalene epoxidase, Squalene monooxygenase

Molecular weight (observed) : 64 kDa

Reactivity Species: Human, Mouse, Rat

Tested Application: ELISA, WB, IHC

Recomended Dillution : WB: 1:200-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200

Research Area: Metabolism