Anti-ST2 Capture Antibody | A2098

Suppressor of tumorigenicity (ST2) belongs to the interleukin 1 family of receptors. It exists in two isoforms: soluble form (sST2) found circulating in the plasma and transmembrane receptor form (ST2L). This protein is expressed by cardiomyocytes and vascular endothelial cells. Binding of ST2L to its ligand IL-33, prevents hypertrophy of the myocardium and fibrosis. However, sST2 competes with ST2L to bind to IL-33 and upon binding its ligand, neutralizes the cardioprotective effects of IL-33 and ST2L. Elevated levels of sST2 are associated with ventricular remodeling, fibrosis and chronic heart failure.

A2098 | Anti-ST2 Capture Antibody DataSheet

Antibody Target: ST2

Target Alternative Name:

Tag Line: Protein A purified mouse monoclonal antibody to detect ST2 in humans. This antibody is match-paired with Anti-ST2 Detection Antibody (Catalog# A2099) and can be used for applications such as ELISA, Lateral Flow and Chemiluminescence immunoassay (CLIA)

Category: Primary antibody

Host: Mouse

Isotype: IgG1

Species Reactivities: Human

Immunogen Sequence: Recombinant ST2

Accession #:

Gene ID:

Appearance: Colorless liquid

Form: Liquid

Concentration:

Formulation: In 10 mM PBS, pH 7.4, 0.02% Proclin 300

Purification: Protein A purified

Application: Lateral Flow,CLIA,ELISA

Positive Control:

Application And Usages: ELISA, Lateral Flow, CLIA

Country of Animal Origin: USA

Country of Manufacture: USA

Usage: For Research Use Only! Not to be used in humans.

Handling: The antibody solution should be gently mixed before use.

Western Blot Verified: False

Immunocytochemistry Verified: False

Immunofluorescence Verified: False

Immunoprecipitation Verified: False

FACS Verified: False

ELISA Verified: True

ChIP Verified: False

Dot Blot Verified: False

Flow Cytometry Verified: False