710
Anti- STAM2 Antibody | FNab08284
- SKU:
- 710-FNab08284-GEN
- Availability:
- In Stock - Delivery within a week
Description
Anti- STAM2 Antibody | FNab08284 | Gentaur UK, US & Europe Distribution
Form: liquid
Purification: Immunogen affinity purified
Purity: ≥95% as determined by SDS-PAGE
Host: Rabbit
Clonality: polyclonal
Clone ID: N/A
Isotype: IgG
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background: Involved in intracellular signal transduction mediated by cytokines and growth factors. Upon IL-2 and GM-CSL stimulation, it plays a role in signaling leading to DNA synthesis and MYC induction. May also play a role in T-cell development. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with HGS (ESCRT-0 complex) . The ESCRT-0 complex binds ubiquitin and acts as sorting machinery that recognizes ubiquitinated receptors and transfers them to further sequential lysosomal sorting/trafficking processes (By similarity) .
Immunogen: signal transducing adaptor molecule (SH3 domain and ITAM motif) 2
synonyms: HBP
Molecular weight (observed) : 68 kDa
Reactivity Species: Human, Mouse, Rat
Tested Application: ELISA, WB, IF, IP
Recomended Dillution : WB: 1:500-1:2000; IP: 1:200-1:2000
Research Area: Epigenetics, Signal Transduction