Anti-STAT1 monoclonal Antibody | MB62424

Anti-STAT1 monoclonal Antibody | MB62424 | Gentaur UK, US & Europe Distribution

Host: Mouse

Reactivity: Human, Mouse, Rat

Application: IF, WB

Application Range: WB 1:2000 IHC 1:50 IF 1:100

Background: The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens. Two alternatively spliced transcript variants encoding distinct isoforms have been described.

Storage & Stability: PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Specificity: signal transducer and activator of transcription 1

Molecular Weight: 91 kDa (Predicted)

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: CANDF7; IMD31A; IMD31B; IMD31C; ISGF-3; STAT91

Immunogen: Full-length protein expressed in 293T cell transfected with human STAT1 expression vector

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Pathway: N/A