26
Anti-STAT5B Antibody | A1753
- SKU:
- 26-A1753-100-GEN
- Availability:
- Usually shipped in 5 working days
Description
The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein mediates the signal transduction triggered by various cell ligands, such as IL2, IL4, CSF1, and different growth hormones. It has been shown to be involved in diverse biological processes, such as TCR signaling, apoptosis, adult mammary gland development, and sexual dimorphism of liver gene expression. This gene was found to fuse to retinoic acid receptor-alpha (RARA) gene in a small subset of acute promyelocytic leukemias (APLL). The dysregulation of the signaling pathways mediated by this protein may be the cause of the APLL.
A1753 | Anti-STAT5B Antibody DataSheet
Antibody Target: Signal transducer and activator of transcription 5B
Target Alternative Name: Signal transducer and activator of transcription 5B, Transcription factor STAT5B
Tag Line: Polyclonal antibody to detect STAT5B in human mouse and rat sample.
Category: Signal Transduction
Host: Rabbit
Isotype: IgG
Species Reactivities: Rat, Mouse, Human
Immunogen Sequence: Recombinant protein of human STAT5B
Accession #: P51692
Gene ID: 6777
Appearance: Colorless liquid
Form: Liquid
Concentration: 0.4 mg/ml
Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Purification: Affinity purification
Application: Immunohistochemistry (IHC), ELISA
Positive Control:
Application And Usages: IHC 1:10-1:50
Country of Animal Origin: USA
Country of Manufacture: USA
Usage: For Research Use Only! Not to be used in humans.
Handling: The antibody solution should be gently mixed before use.
Western Blot Verified: False
Immunocytochemistry Verified: True
Immunofluorescence Verified: False
Immunoprecipitation Verified: False
FACS Verified: False
ELISA Verified: False
ChIP Verified: False
Dot Blot Verified: False
Flow Cytometry Verified: False
Additional Information
Size: |
100 uL |
Storage Condition: |
-20°C |
Shipping Condition: |
Gel Pack |
Shelf Life: |
12 months |