Anti-STRADA Antibody | A1868

The protein encoded by this gene contains a STE20-like kinase domain, but lacks several residues that are critical for catalytic activity, so it is termed a 'pseudokinase'. The protein forms a heterotrimeric complex with serine/threonine kinase 11 (STK11, also known as LKB1) and the scaffolding protein calcium binding protein 39 (CAB39, also known as MO25). The protein activates STK11 leading to the phosphorylation of both proteins and excluding STK11 from the nucleus. The protein is necessary for STK11-induced G1 cell cycle arrest. A mutation in this gene has been shown to result in polyhydramnios, megalencephaly, and symptomatic epilepsy (PMSE) syndrome. Multiple transcript variants encoding different isoforms have been found for this gene. Additional transcript variants have been described but their full-length nature is not known.

A1868 | Anti-STRADA Antibody DataSheet

Antibody Target: STRADA

Target Alternative Name: Stlk, PMSE, STE20-related kinase adaptor alpha, STRADA, STRAD, LYK5, NY-BR-96

Tag Line: Affinity purified Rabbit polyclonal to STRADA

Category: Primary antibody

Host: Rabbit

Isotype: Rabbit IgG

Species Reactivities: Mouse

Immunogen Sequence: Recombinant fusion protein containing a sequence corresponding to amino acids 25-210 of human STRADA (NP_699166.2).

Accession #: Q7RTN6

Gene ID: 92335

Appearance: Liquid

Form: Liquid

Concentration:

Formulation: Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification: Affinity Purification

Application: Western Blotting

Positive Control:

Application And Usages: WB 1:1000 - 1:2000

Country of Animal Origin: USA

Country of Manufacture: USA

Usage: For Research Use Only! Not to be used in humans.

Handling: The antibody solution should be gently mixed before use.

Western Blot Verified: True

Immunocytochemistry Verified: False

Immunofluorescence Verified: False

Immunoprecipitation Verified: False

FACS Verified: False

ELISA Verified: False

ChIP Verified: False

Dot Blot Verified: False

Flow Cytometry Verified: False