Anti- TBP Antibody | FNab08526

Anti- TBP Antibody | FNab08526 | Gentaur UK, US & Europe Distribution

Form: liquid

Purification: Immunogen affinity purified

Purity: ≥95% as determined by SDS-PAGE

Host: Rabbit

Clonality: polyclonal

Clone ID: N/A

Isotype: IgG

Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background: General transcription factor that functions at the core of the DNA-binding multiprotein factor TFIID. Binding of TFIID to the TATA box is the initial transcriptional step of the pre-initiation complex (PIC), playing a role in the activation of eukaryotic genes transcribed by RNA polymerase II. Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (preinitiation complex) during RNA polymerase I-dependent transcription. The rate of PIC formation probably is primarily dependent on the rate of association of SL1 with the rDNA promoter. SL1 is involved in stabilization of nucleolar transcription factor 1/UBTF on rDNA.

Immunogen: TATA box binding protein

synonyms: GTF2D1, TF2D, TFIID

Molecular weight (observed) : human 37-43kDa

Reactivity Species: Human, Mouse

Tested Application: ELISA, WB, IP

Recomended Dillution : WB: 1:500-1:2000; IF: 1:20-1:200

Research Area: Neuroscience, Metabolism, Developmental biology