Anti- TFEB Antibody | FNab08627

Anti- TFEB Antibody | FNab08627 | Gentaur UK, US & Europe Distribution

Form: liquid

Purification: Immunogen affinity purified

Purity: ≥95% as determined by SDS-PAGE

Host: Rabbit

Clonality: polyclonal

Clone ID: N/A

Isotype: IgG

Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background: TFEB specifically recognizes and binds to E-box sequences, which required dimerization with itself or another MiT/TFE family member. It plays a role in T-cell-dependent antibody responses to activated CD4+ T-cells and thymus-dependent humoral immunity once associated with TFE3. It also activates lysosomal gene by binding the CLEAR-box sequence in the regulatory region. It involves in the signal transduction processes required for normal vascularization of the placenta. This is a rabbit polyclonal antibody raised against the full length of human TFEB. The calcualted molecular weight of TFEB is 53 kDa, but modified TFEB is about 65-70 kDa.

Immunogen: transcription factor EB

synonyms: AlphaTFEB, bHLHe35, TCFEB, TFEB, transcription factor EB

Molecular weight (observed) : 65-70kd

Reactivity Species: Human, Mouse, Rat

Tested Application: ELISA, WB, IP, IHC

Recomended Dillution : WB: 1:500-1:2000; IHC: 1:50-1:200; IF: 1:20-1:200

Research Area: Metabolism