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Anti-TMPRSS2 Antibody | A2102
- SKU:
- 26-A2102-100-GEN
- Availability:
- Usually shipped in 5 working days
Description
This gene encodes a protein that belongs to the serine protease family. The encoded protein contains a type II transmembrane domain, a receptor class A domain, a scavenger receptor cysteine-rich domain and a protease domain. Serine proteases are known to be involved in many physiological and pathological processes. This gene was demonstrated to be up-regulated by androgenic hormones in prostate cancer cells and down-regulated in androgen-independent prostate cancer tissue. The protease domain of this protein is thought to be cleaved and secreted into cell media after autocleavage. This protein also facilitates entry of viruses into host cells by proteolytically cleaving and activating viral envelope glycoproteins. Viruses found to use this protein for cell entry include Influenza virus and the human coronaviruses HCoV-229E, MERS-CoV, SARS-CoV and SARS-CoV-2 (COVID-19 virus). Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
A2102 | Anti-TMPRSS2 Antibody DataSheet
Antibody Target: TMPRSS2
Target Alternative Name: 5A11 antigen; 5F7; Basigin; Blood brain barrier HT7 antigen; Bsg; CD 147; CD147; CD147 antigen; Collagenase stimulatory factor; EMMPRIN; Extracellular matrix metalloproteinase inducer; Leukocyte activation antigen M6; M 6; M6; M6 leukocyte activation antigen; Neurothelin; OK; OK blood group; OK blood group antigen; TCSF; Tumor cell derived collagenase stimulatory factor; Tumor cell-derived collagenase stimulatory factor
Tag Line: Affinity purified rabbit polyclonal antibody to detect the expression of Transmembrane serine protease 2 in human, mouse and rat samples
Category: Primary antibody
Host: Rabbit
Isotype: IgG
Species Reactivities: Mouse,Human
Immunogen Sequence: Recombinant full length protein of human TMPRSS2
Accession #:
Gene ID: 7113
Appearance: Colorless liquid
Form: Liquid
Concentration:
Formulation: In 0.42% Potassium phosphate; 0.87% NaCl; pH 7.3; 30% glycerol; and 0.01% sodium azide
Purification: Affinity purified
Application: Immunohistochemistry (IHC),Western Blotting
Positive Control:
Application And Usages: WB 1:500-1:1000, IHC 1:100-1:200
Country of Animal Origin: USA
Country of Manufacture: USA
Usage: For Research Use Only! Not to be used in humans.
Handling: The antibody solution should be gently mixed before use.
Western Blot Verified: TRUE
Immunocytochemistry Verified: FALSE
Immunofluorescence Verified: FALSE
Immunoprecipitation Verified: FALSE
FACS Verified: FALSE
ELISA Verified: FALSE
ChIP Verified: FALSE
Dot Blot Verified: FALSE
Flow Cytometry Verified: FALSE
Additional Information
Size: |
100 uL |
Storage Condition: |
-20ºC |
Shipping Condition: |
Gel Pack |
Shelf Life: |
12 months |