Anti- TRPV5 Antibody | FNab09029

Anti- TRPV5 Antibody | FNab09029 | Gentaur UK, US & Europe Distribution

Form: liquid

Purification: Immunogen affinity purified

Purity: ≥95% as determined by SDS-PAGE

Host: Rabbit

Clonality: polyclonal

Clone ID: N/A

Isotype: IgG

Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background: Constitutively active calcium selective cation channel thought to be involved in Ca (2+) reabsorption in kidney and intestine (PubMed:11549322, PubMed:18768590) . Required for normal Ca (2+) reabsorption in the kidney distal convoluted tubules (By similarity) . The channel is activated by low internal calcium level and the current exhibits an inward rectification (PubMed:11549322, PubMed:18768590) . A Ca (2+) -dependent feedback regulation includes fast channel inactivation and slow current decay (By similarity) . Heteromeric assembly with TRPV6 seems to modify channel properties. TRPV5-TRPV6 heteromultimeric concatemers exhibit voltage-dependent gating (By similarity) .

Immunogen: transient receptor potential cation channel, subfamily V, member 5

synonyms: Calcium transport protein 2, CAT2, ECaC, ECAC1, Epithelial calcium channel 1, Osm 9 like TRP channel 3, OTRPC3, TRPV5

Molecular weight (observed) : 43 kDa

Reactivity Species: Human, Mouse, Rat

Tested Application: ELISA, WB

Recomended Dillution : IF: 1:10-1:100

Research Area: Epigenetics, Metabolism