Anti- UBE2C Antibody | FNab09166

Anti- UBE2C Antibody | FNab09166 | Gentaur UK, US & Europe Distribution

Form: liquid

Purification: Protein A+G purification

Purity: ≥95% as determined by SDS-PAGE

Host: Mouse

Clonality: monoclonal

Clone ID: 7E3

Isotype: IgG1

Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background: Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-11'-and 'Lys-48'-linked polyubiquitination. Acts as an essential factor of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated ubiquitin ligase that controls progression through mitosis. Acts by initiating 'Lys-11'-linked polyubiquitin chains on APC/C substrates, leading to the degradation of APC/C substrates by the proteasome and promoting mitotic exit.

Immunogen: ubiquitin-conjugating enzyme E2C

synonyms: DJ447F3.2, UBCH10, UBE2C, Ubiquitin carrier protein C, Ubiquitin protein ligase C

Molecular weight (observed) : 17 kDa

Reactivity Species: Human

Tested Application: ELISA, WB, IHC, IF, IP

Recomended Dillution : WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:10-1:100

Research Area: Epigenetics, Metabolism