Anti- ULK1 Antibody | FNab09251

Anti- ULK1 Antibody | FNab09251 | Gentaur UK, US & Europe Distribution

Form: liquid

Purification: Immunogen affinity purified

Purity: ≥95% as determined by SDS-PAGE

Host: Rabbit

Clonality: polyclonal

Clone ID: N/A

Isotype: IgG

Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background: ULK1, also named as KIAA0722, belongs to the protein kinase superfamily, Ser/Thr protein kinase family and APG1/unc-51/ULK1 subfamily. It is involved in autophagy. ULK1 is required for autophagosome formation. It forms a stable complex with Atg13 and focal adhesion kinase (FAK) family interacting protein of 200 kDa (FIP 200) (PMID:21460634) . ULK1 phosphorylates ATG13/KIAA0652. It is involved in axon growth. ULK1 plays an essential role in neurite extension of cerebellar granule cells. ULK1 represents a potential novel prognostic biomarker for HCC patients and may play an important role during the progression of HCC (PMID:23573318) .

Immunogen: unc-51-like kinase 1 (C. elegans)

synonyms: ATG1, FLJ38455, FLJ46475, KIAA0722, ULK1, Unc 51 like kinase 1, UNC51, Unc51.1

Molecular weight (observed) : 150 kDa

Reactivity Species: Human, Rat

Tested Application: ELISA, WB

Recomended Dillution : WB: 1:200-1:1000; IHC: 1：50-1：500

Research Area: Cardiovascular, Metabolism, Developmental biology, Signal Transduction