Anti-Adenovirus antibody

Mouse monoclonal to Adenovirus

Mouse

This antibody recognises all Adenovirus serotypes; binding to the hexon polypeptide. No cross-reactions are known.

Suitable for: IHC-P, ELISA, IHC-Fr

Reacts with: Adenovirus

Tissue, cells or virus corresponding to Adenovirus Adenovirus. Adenovirus type 3 (ATCC strain VR847)

With recent studies indicating that viral agents may be implicated in new emerging diseases reported around the world, interest in viruses has increased and encompassed many different viral genera. The adenoviruses are represented by several different groups yet there are only few monoclonal antibodies that are commercially available that recognise all known serotypes.

Adenoviruses are DNA viruses generally widespread in nature that are frequently the cause of acute upper respiratory tract infections (i.e. common colds). Forty-seven known serotypes have been isolated since they were first discovered in 1953 with 3 types known to cause gastroenteritis. Several types have oncogenic potential though most cause self-limiting febrile illnesses characterised by inflammation of conjunctivae and the respiratory tract. The virus can be isolated from the majority of tonsils/adenoids surgically removed, indicating latent infections. It is not known how long the virus can persist in the body, or whether it is capable of reactivation after long periods. In patients experiencing immunosuppression (e.g. AIDS) it can be reactivated causing disease.

 

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