Anti- USP1 Antibody | FNab09303

Anti- USP1 Antibody | FNab09303 | Gentaur UK, US & Europe Distribution

Form: liquid

Purification: Protein A+G purification

Purity: ≥95% as determined by SDS-PAGE

Host: Mouse

Clonality: monoclonal

Clone ID: 8F7

Isotype: IgG1

Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background: Negative regulator of DNA damage repair which specifically deubiquitinates monoubiquitinated FANCD2 (PubMed:15694335) . Also involved in PCNA-mediated translesion synthesis (TLS) by deubiquitinating monoubiquitinated PCNA (PubMed:16531995) . Has almost no deubiquitinating activity by itself and requires the interaction with WDR48 to have a high activity (PubMed:18082604, PubMed:26388029) .

Immunogen: ubiquitin specific peptidase 1

synonyms: Deubiquitinating enzyme 1, hUBP, ubiquitin specific peptidase 1, Ubiquitin thiolesterase 1, UBP, USP1

Molecular weight (observed) : 90 kDa

Reactivity Species: Human

Tested Application: ELISA, WB, IHC, IP

Recomended Dillution : WB: 1:1000-1:10000; IHC: 1:20-1:200

Research Area: Epigenetics, Metabolism