710
Anti- USP14 Antibody | FNab09310
- SKU:
- 710-FNab09310-GEN
- Availability:
- In Stock - Delivery within a week
Description
Anti- USP14 Antibody | FNab09310 | Gentaur UK, US & Europe Distribution
Form: liquid
Purification: Immunogen affinity purified
Purity: ≥95% as determined by SDS-PAGE
Host: Rabbit
Clonality: polyclonal
Clone ID: N/A
Isotype: IgG
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background: Proteasome-associated deubiquitinase which releases ubiquitin from the proteasome targeted ubiquitinated proteins. Ensures the regeneration of ubiquitin at the proteasome. Is a reversibly associated subunit of the proteasome and a large fraction of proteasome-free protein exists within the cell. Required for the degradation of the chemokine receptor CXCR4 which is critical for CXCL12-induced cell chemotaxis. Serves also as a physiological inhibitor of endoplasmic reticulum-associated degradation (ERAD) under the non-stressed condition by inhibiting the degradation of unfolded endoplasmic reticulum proteins via interaction with ERN1. Indispensable for synaptic development and function at neuromuscular junctions (NMJs) .
Immunogen: ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)
synonyms: Deubiquitinating enzyme 14, TGT, Ubiquitin thiolesterase 14, USP14
Molecular weight (observed) : 52-60 kDa
Reactivity Species: Human, Mouse, Rat
Tested Application: ELISA, WB, IHC, IF
Recomended Dillution : WB: 1:500-1:5000; IP: 1:500-1:5000; IF: 1:10-1:100
Research Area: Epigenetics, Metabolism