Anti- Vinculin Antibody | FNab09800

Anti- Vinculin Antibody | FNab09800 | Gentaur UK, US & Europe Distribution

Form: liquid

Purification: Protein A+G purification

Purity: ≥95% as determined by SDS-PAGE

Host: Mouse

Clonality: monoclonal

Clone ID: 5E7

Isotype: IgG1

Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background: Vinculin belongs to the vinculin/alpha-catenin family. It is an actin filament (F-actin) -binding protein which involved in cell-matrix adhesion and cell-cell adhesion. Vinculin regulates cell-surface E-cadherin expression and potentiates mechanosensing by the E-cadherin complex. It may also play important roles in cell morphology and locomotion. Vinculin is a 117-kDa, 1, 066-amino-acid protein which is ubiquitously expressed. Its splice variant, metavinculin (124 kDa), is muscle-specific.

Immunogen: vinculin

synonyms: CMD1W, Metavinculin, MVCL, VCL, Vinculin

Molecular weight (observed) : 124 kDa

Reactivity Species: Human, Rat, Mouse

Tested Application: ELISA, IHC, WB

Recomended Dillution : WB: 1:2000-1:20000; IHC: 1:50-1:500; IF: 1:50-1:500

Research Area: Immunology, Cardiovascular