Anti- VPS33B Antibody | FNab09436

Anti- VPS33B Antibody | FNab09436 | Gentaur UK, US & Europe Distribution

Form: liquid

Purification: Immunogen affinity purified

Purity: ≥95% as determined by SDS-PAGE

Host: Rabbit

Clonality: polyclonal

Clone ID: N/A

Isotype: IgG

Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background: May play a role in vesicle-mediated protein trafficking to lysosomal compartments and in membrane docking/fusion reactions of late endosomes/lysosomes. Mediates phagolysosomal fusion in macrophages (PubMed:18474358) . Proposed to be involved in endosomal maturation implicating VIPAS39. In epithelial cells, the VPS33B:VIPAS39 complex may play a role in the apical recycling pathway and in the maintenance of the apical-basolateral polarity (PubMed:20190753) . Seems to be involved in the sorting of specific cargos from the trans-Golgi network to alpha-granule-destined multivesicular bodies (MVBs) promoting MVBs maturation in megakaryocytes (By similarity) .

Immunogen: vacuolar protein sorting 33 homolog B (yeast)

synonyms: FLJ14848, hVPS33B, VPS33B

Molecular weight (observed) : 71 kDa

Reactivity Species: Human, Mouse, Rat, Zebrafish

Tested Application: ELISA, WB

Recomended Dillution : WB: 1:500-1:2000; IHC: 1:50-1:200; IF: 1:10-1:100

Research Area: Signal Transduction