Anti- VPS52 Antibody | FNab09447

Anti- VPS52 Antibody | FNab09447 | Gentaur UK, US & Europe Distribution

Form: liquid

Purification: Immunogen affinity purified

Purity: ≥95% as determined by SDS-PAGE

Host: Rabbit

Clonality: polyclonal

Clone ID: N/A

Isotype: IgG

Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background: Acts as component of the GARP complex that is involved in retrograde transport from early and late endosomes to the trans-Golgi network (TGN) . The GARP complex is required for the maintenance of the cycling of mannose 6-phosphate receptors between the TGN and endosomes, this cycling is necessary for proper lysosomal sorting of acid hydrolases such as CTSD (PubMed:15878329, PubMed:18367545) . Acts as component of the EARP complex that is involved in endocytic recycling. The EARP complex associates with Rab4-positive endosomes and promotes recycling of internalized transferrin receptor (TFRC) to the plasma membrane (PubMed:25799061) .

Immunogen: vacuolar protein sorting 52 homolog (S. cerevisiae)

synonyms: ARE1, dJ1033B10.5, DKFZp547I194, RP5 1033B10, SAC2, SACM2L, VPS52

Molecular weight (observed) : 82 kDa

Reactivity Species: Human, Mouse, Rat

Tested Application: ELISA, WB, IF, IP

Recomended Dillution : WB: 1:200-1:2000；IP: 1:500-1:5000；IHC: 1:20-1:200; IF: 1:10-1:100

Research Area: Signal Transduction