710
Anti- VPS53 Antibody | FNab09448
- SKU:
- 710-FNab09448-GEN
- Availability:
- In Stock - Delivery within a week
Description
Anti- VPS53 Antibody | FNab09448 | Gentaur UK, US & Europe Distribution
Form: liquid
Purification: Immunogen affinity purified
Purity: ≥95% as determined by SDS-PAGE
Host: Rabbit
Clonality: polyclonal
Clone ID: N/A
Isotype: IgG
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background: Acts as component of the GARP complex that is involved in retrograde transport from early and late endosomes to the trans-Golgi network (TGN) . The GARP complex is required for the maintenance of the cycling of mannose 6-phosphate receptors between the TGN and endosomes, this cycling is necessary for proper lysosomal sorting of acid hydrolases such as CTSD (PubMed:15878329, PubMed:18367545) . Acts as component of the EARP complex that is involved in endocytic recycling. The EARP complex associates with Rab4-positive endosomes and promotes recycling of internalized transferrin receptor (TFRC) to the plasma membrane (PubMed:25799061) .
Immunogen: vacuolar protein sorting 53 homolog (S. cerevisiae)
synonyms: FLJ10979, HCCS1, hVps53L, pp13624, VPS53
Molecular weight (observed) : 96 kDa
Reactivity Species: Human, Mouse, Rat
Tested Application: ELISA, WB, IHC, IF, IP
Recomended Dillution : WB: 1:500-1:5000;IP: 1:200-1:2000
Research Area: Signal Transduction