Anti- WDR1 Antibody | FNab09481

Anti- WDR1 Antibody | FNab09481 | Gentaur UK, US & Europe Distribution

Form: liquid

Purification: Immunogen affinity purified

Purity: ≥95% as determined by SDS-PAGE

Host: Rabbit

Clonality: polyclonal

Clone ID: N/A

Isotype: IgG

Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background: Induces disassembly of actin filaments in conjunction with ADF/cofilin family proteins (PubMed:15629458) . Enhances cofilin-mediated actin severing (By similarity) . Involved in cytokinesis. Involved in chemotactic cell migration by restricting lamellipodial membrane protrusions (PubMed:18494608) . Involved in myocardium sarcomere organization. Required for cardiomyocyte growth and maintenance (By similarity) . Involved in megakaryocyte maturation and platelet shedding. Required for the establishment of planar cell polarity (PCP) during follicular epithelium development and for cell shape changes during PCP; the function seems to implicate cooperation with CFL1 and/or DSTN/ADF. Involved in the generation/maintenance of cortical tension (By similarity) . Involved in assembly and maintenance of epithelial apical cell junctions and plays a role in the organization of the perijunctional actomyosin belt (PubMed:25792565) .

Immunogen: WD repeat domain 1

synonyms: Actin interacting protein 1, AIP1, NORI 1, WD repeat containing protein 1, WD repeat domain 1, WDR1

Molecular weight (observed) : 66 kDa

Reactivity Species: Human, Mouse, Rat

Tested Application: ELISA, IHC

Recomended Dillution : WB: 1:200-1:2000; IP: 1:200-1:2000; IHC: 1:20-1:200

Research Area: Neuroscience