Anti- WT1 Antibody | FNab09528

Anti- WT1 Antibody | FNab09528 | Gentaur UK, US & Europe Distribution

Form: liquid

Purification: Immunogen affinity purified

Purity: ≥95% as determined by SDS-PAGE

Host: Rabbit

Clonality: polyclonal

Clone ID: N/A

Isotype: IgG

Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background: Transcription factor that plays an important role in cellular development and cell survival. Regulates the expression of numerous target genes, including EPO. Plays an essential role for development of the urogenital system. Recognizes and binds to the DNA sequence 5'-CGCCCCCGC-3'. It has a tumor suppressor as well as an oncogenic role in tumor formation. Function may be isoform-specific: isoforms lacking the KTS motif may act as transcription factors. Isoforms containing the KTS motif may bind mRNA and play a role in mRNA metabolism or splicing. Isoform 1 has lower affinity for DNA, and can bind RNA.

Immunogen: Wilms tumor 1

synonyms: GUD, WAGR, Wilms tumor 1, Wilms tumor protein, WIT 2, WT1, WT33

Molecular weight (observed) : 52 kDa

Reactivity Species: Human, Mouse, Rat

Tested Application: ELISA, WB, IHC, IF, IP

Recomended Dillution : WB: 1:500-1:5000; IHC: 1:50-1:500; IF: 1:20-1:200; IP: 1:500-1:5000

Research Area: Metabolism, Immunology, Cancer, Developmental biology, Stem Cells