710
Anti- WWP1 Antibody | FNab09534
- SKU:
- 710-FNab09534-GEN
- Availability:
- In Stock - Delivery within a week
Description
Anti- WWP1 Antibody | FNab09534 | Gentaur UK, US & Europe Distribution
Form: liquid
Purification: Immunogen affinity purified
Purity: ≥95% as determined by SDS-PAGE
Host: Rabbit
Clonality: polyclonal
Clone ID: N/A
Isotype: IgG
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background: E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Ubiquitinates ERBB4 isoforms JM-A CYT-1 and JM-B CYT-1, KLF2, KLF5 and TP63 and promotes their proteasomal degradation. Ubiquitinates RNF11 without targeting it for degradation. Ubiquitinates and promotes degradation of TGFBR1; the ubiquitination is enhanced by SMAD7. Ubiquitinates SMAD6 and SMAD7. Ubiquitinates and promotes degradation of SMAD2 in response to TGF-beta signaling, which requires interaction with TGIF.
Immunogen: WW domain containing E3 ubiquitin protein ligase 1
synonyms: AIP5, DKFZp434D2111, hSDRP1, Tiul1, WW domain containing protein 1, WWP1
Molecular weight (observed) : 95 kDa
Reactivity Species: Human, Mouse, Rat
Tested Application: ELISA, WB
Recomended Dillution : WB: 1:200-1:2000; IP: 1:200-1:1000; IF: 1:20-1:200
Research Area: Epigenetics, Signal Transduction, Metabolism