710
Anti- XPG Antibody | FNab09547
- SKU:
- 710-FNab09547-GEN
- Availability:
- In Stock - Delivery within a week
Description
Anti- XPG Antibody | FNab09547 | Gentaur UK, US & Europe Distribution
Form: liquid
Purification: Immunogen affinity purified
Purity: ≥95% as determined by SDS-PAGE
Host: Rabbit
Clonality: polyclonal
Clone ID: N/A
Isotype: IgG
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background: The human genes correcting DNA repair defects are termed excision-repair cross-complementing or ERCC genes. The ERCC5 gene corrects the excision repair deficiency of Chinese hamster ovary cell line UV135 of complementation group 5. The human ERCC5 gene product is a structure-specific endonuclease required for making the 3-prime incision during DNA nucleotide excision-repair (NER) . It also plays an important role in regulating DNA excision repair, removal of bulky lesions caused by environmental chemicals or UV light [PMID:22815677].
Immunogen: excision repair cross-complementing rodent repair deficiency, complementation group 5
synonyms: COFS3, ERCC5, ERCM2, UVDR, XPG, XPGC
Molecular weight (observed) : 200 kDa
Reactivity Species: Human
Tested Application: ELISA, WB
Recomended Dillution : WB: 1:200-1:2000; IF: 1:20-1:200; IP: 1:200-1:2000
Research Area: Epigenetics, Metabolism