Anti- ZFYVE19 Antibody | FNab09629

Anti- ZFYVE19 Antibody | FNab09629 | Gentaur UK, US & Europe Distribution

Form: liquid

Purification: Immunogen affinity purified

Purity: ≥95% as determined by SDS-PAGE

Host: Rabbit

Clonality: polyclonal

Clone ID: N/A

Isotype: IgG

Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background: Key regulator of abscission step in cytokinesis: part of the cytokinesis checkpoint, a process required to delay abscission to prevent both premature resolution of intercellular chromosome bridges and accumulation of DNA damage. Together with CHMP4C, required to retain abscission-competent VPS4 (VPS4A and/or VPS4B) at the midbody ring until abscission checkpoint signaling is terminated at late cytokinesis. Deactivation of AURKB results in dephosphorylation of CHMP4C followed by its dissociation from ZFYVE19/ANCHR and VPS4 and subsequent abscission.

Immunogen: zinc finger, FYVE domain containing 19

synonyms: FLJ14840, MPFYVE, ZFYVE19

Molecular weight (observed) : 52 kDa

Reactivity Species: Human

Tested Application: ELISA, WB, IP, IHC

Recomended Dillution : WB: 1:1000-1:10000; IHC: 1:20-1:200

Research Area: Metabolism