Antimycin A | 2247

Antimycin A, isolated from Streptomyces sp., is a mixture of Antimycins A1, A2, A3 and A4. Inhibits mitochondrial electron transport, specifically between cytochromes b and c1. Induces apoptosis, which is not prevented by the presence of Bcl-2.

Antimycin A is an inhibitor of mitochondrial electron transport, specifically between cytochromes b and c1.

2247 | Antimycin A DataSheet

Alternate Name/Synonyms: Antipiricullin, Virosin

Appearance: White to yellow solid

Formulation: N/A

CAS Number: 1397-94-0

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₈H₄₀N₂O₉

Molecular Weight: 548.63

Cell-Permeable?: No

Purity: ≥95% by HPLC

Solubilities: EtOH (50 mg/ml)

Handling: Protect from light and moisture

Country of Origin: USA

Tag Line: A mitochondrial electron transport inhibitor

MDL Number: MFCD01779723

PubChem CID: 14957

SMILES: CCCCCCC1C(C(OC(=O)C(C(OC1=O)C)NC(=O)C2=C(C(=CC=C2)NC=O)O)C)OC(=O)CC(C)C

InChi: InChI=1S/C28H40N2O9/c1-6-7-8-9-11-20-25(39-22(32)14-16(2)3)18(5)38-28(36)23(17(4)37-27(20)35)30-26(34)19-12-10-13-21(24(19)33)29-15-31/h10,12-13,15-18,20,23,25,33H,6-9,11,14H2,1-5H3,(H,29,31)(H,30,34)/t17-,18+,20-,23+,25+/m1/s1

InChi Key: UIFFUZWRFRDZJC-SBOOETFBSA-N