APC Anti-Human CD80 Antibody[2D10] | E-AB-F1232E

APC Anti-Human CD80 Antibody[2D10] | E-AB-F1232E | Gentaur UK, US & Europe Distribution

Category: Flow Cytometry Antibody

Synonyms: T-lymphocyte activation antigen CD80,B7-1, B7, BB1

Swissprot Code: P33681

Application: FCM

Reactivity: Human

Host: Mouse

Isotype: Mouse IgG1, κ

Reaserch Area: Cancer, Immunology, Stem cells

Background: CD80 is a 60 kD highly glycosylated protein. It is a member of the Ig superfamily and is also known as B7-1, B7, and Ly-53. CD80 is constitutively expressed on dendritic cells and monocytes/macrophages, and inducibly expressed on activated B and T cells. The ligation of CD28 on T cells with CD80 and CD86 (B7-2) on antigen presenting cells (such as dendritic cells, macrophages, and B cells) elicits co-stimulation of T cells resulting in enhanced cell activation, proliferation, and cytokine production. CD80 appears to be expressed later in the immune response than CD86. CD80 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells.

Concentration: N/A

Storage: Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.

Immunogen: N/A

Purification Method: N/A

Dilution: N/A

Clone: 2D10

Conjugation: APC