APC Anti-Human IL-21 Antibody[3A3-N2] | E-AB-F1202E

APC Anti-Human IL-21 Antibody[3A3-N2] | E-AB-F1202E | Gentaur UK, US & Europe Distribution

Category: Flowcytometry Antibody

Synonyms: Interleukin-21,IL-21,Za11

Swissprot Code: Q9HBE4

Application: ICFCM

Reactivity: Human

Host: Mouse

Isotype: Mouse IgG2a, κ

Research Areas: Cancer, Immunology

Backgroun: Interleukin 21 (IL-21) is a potent immunomodulatory cytokine mainly produced by NKT and CD4+ T-cells, particularly the inflammatory Th17 subset, and has pleiotropic effects on both innate and adaptive immune responses. These actions include positive effects such as enhancing proliferation of NK cells and cytotoxic T cells, and inhibitory effects on the antigen-presenting function of dendritic cells. It can also be proapoptotic for B cells and NK cells. Studies have shown that IL-21 is also an autocrine cytokine that potently induces Th17 differentiation, suppresses Foxp3 expression, and serves as a target for treating inflammatory diseases.

Concentration: N/A

Storage: Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.

Immunogen: N/A

Buffer: PBS with 0.05% Proclin300, 1% BSA

Purification Method: N/A

Dilution: N/A

Clone: 3A3-N2

Conjugation: APC

Moleculair Weight(Calculated): N/A

Moleculair Weight(Observed): N/A