Apixaban | B1855

Apixaban is a potent, selective inhibitor of both free and prothrombinase-bound factor Xa (Ki = 0.8 nM). Apixaban is an effective anticoagulant in both preclinical and clinical models of venous and arterial thrombosis.

Apixaban is a potent, selective inhibitor of both free and prothrombinase-bound factor Xa (Ki = 0.8 nM). Apixaban is an effective anticoagulant in both preclinical and clinical models of venous and arterial thrombosis.

B1855 | Apixaban DataSheet

Alternate Name/Synonyms: 1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4,5-dihydropyrazolo[5,4-c]pyridine-3-carboxamide; BMS56224701

Appearance: White solid

Formulation: N/A

CAS Number: 503612-47-3

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: N/A

Molecular Formula: C₂₅H₂₅N₅O₄

Molecular Weight: 459.5

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A potent, selective inhibitor of both free and prothrombinase-bound factor Xa

MDL Number: N/A

PubChem CID: 10182969

SMILES: COC1=CC=C(C=C1)N2C3=C(CCN(C3=O)C4=CC=C(C=C4)N5CCCCC5=O)C(=N2)C(=O)N

InChi: InChI=1S/C25H25N5O4/c1-34-19-11-9-18(10-12-19)30-23-20(22(27-30)24(26)32)13-15-29(25(23)33)17-7-5-16(6-8-17)28-14-3-2-4-21(28)31/h5-12H,2-4,13-15H2,1H3,(H2,26,32)

InChi Key: QNZCBYKSOIHPEH-UHFFFAOYSA-N