Description
Apixaban is a potent, selective inhibitor of both free and prothrombinase-bound factor Xa (Ki = 0.8 nM). Apixaban is an effective anticoagulant in both preclinical and clinical models of venous and arterial thrombosis.
Apixaban is a potent, selective inhibitor of both free and prothrombinase-bound factor Xa (Ki = 0.8 nM). Apixaban is an effective anticoagulant in both preclinical and clinical models of venous and arterial thrombosis.
Alternate Name/Synonyms: 1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4,5-dihydropyrazolo[5,4-c]pyridine-3-carboxamide; BMS56224701
Appearance: White solid
Formulation: N/A
CAS Number: 503612-47-3
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: N/A
Molecular Formula: C₂₅H₂₅N₅O₄
Molecular Weight: 459.5
Cell-Permeable?: Yes
Purity: ≥98% by HPLC
Solubilities: DMSO
Handling: Protect from air and light
Country of Origin: USA
Tag Line: A potent, selective inhibitor of both free and prothrombinase-bound factor Xa
MDL Number: N/A
PubChem CID: 10182969
SMILES: COC1=CC=C(C=C1)N2C3=C(CCN(C3=O)C4=CC=C(C=C4)N5CCCCC5=O)C(=N2)C(=O)N
InChi: InChI=1S/C25H25N5O4/c1-34-19-11-9-18(10-12-19)30-23-20(22(27-30)24(26)32)13-15-29(25(23)33)17-7-5-16(6-8-17)28-14-3-2-4-21(28)31/h5-12H,2-4,13-15H2,1H3,(H2,26,32)
InChi Key: QNZCBYKSOIHPEH-UHFFFAOYSA-N
Additional Information
Storage Condition: |
-20°C |
Shipping Condition: |
Gel Pack |
Shelf Life: |
36 months |