APOC4 polyclonal Antibody | BS60500

APOC4 polyclonal Antibody | BS60500 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse

Application: WB IHC

Application Range: WB: 1:500~1:1000 IHC: 1:50~1:200

Background: Apolipoproteins are protein components of plasma lipoproteins (1) . The apolipoprotein C gene family encodes four homologous proteins designated apoC-I to -IV, which specifically modulate the metabolism of triglyceride-rich lipoproteins (2) . The human apoC-I gene maps to chromosome 19q13.2 and is expressed primarily in the liver where it is activated when monocytes differentiate into macrophages (3,4) . The human apoC-II gene maps to chromosome 19q13.2 and encodes a 79 amino acid single chain protein that is a necessary cofactor for the activation of lipoprotein lipase, the enzyme that hydrolyzes triglycerides in plasma and transfers the fatty acids to tissues (5–7) . The human apoC-III gene maps to chromosome 11q23 and encodes a protein that may delay catabolism of triglyceride-rich particles by inhibiting lipoprotein lipase and hepatic lipase (8) . The human apoC-IV gene maps to chromosome 19q13.2 and encodes a 127 amino acid protein that is primarily expressed in the liver (9,10) .

Storage & Stability: Store at 4°C short term. Aliquot and store at -30°C long term. Avoid freeze-thaw cycles.

Specificity: APOC4 polyclonal Antibody detects endogenous levels of APOC4 protein.

Molecular Weight: ~ 15 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Apolipoprotein C-IV; Apo-CIV; ApoC-IV; Apolipoprotein C4; APOC4

Immunogen: A synthetic peptide corresponding to residues in Human APOC4.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 105% (by SDS-PAGE) .

Pathway: