Arachidonoyl 2'-Chloroethylamide | B3015

Arachidonyl-2-chloroethylamide (ACEA) is a high affinity agonist of cannabinoid receptor CB1. It binds to the CB1 receptor with high affinity (Ki value of 1.4 nM) and to the CB2 receptor with low affinity (Ki value of 3.1 μM). It inhibits forskolin-induced accumulation of cAMP in Chinese hamster ovary cells expressing the human CB1 receptor. It increases the binding of [35S]GTPgammaS to cerebellar membranes and inhibits electrically evoked contractions of the mouse vas deferens. It produces hypothermia in mice.

Arachidonyl-2-chloroethylamide (ACEA) is a high affinity agonist of cannabinoid receptor CB1. It binds to the CB1 receptor with high affinity (Ki value of 1.4 nM) and to the CB2 receptor with low affinity (Ki value of 3.1 μM). It inhibits forskolin-induced accumulation of cAMP in Chinese hamster ovary cells expressing the human CB1 receptor. It increases the binding of [35S]GTPgammaS to cerebellar membranes and inhibits electrically evoked contractions of the mouse vas deferens. It produces hypothermia in mice.

B3015 | Arachidonoyl 2'-Chloroethylamide DataSheet

Alternate Name/Synonyms: ACEA; (5Z,8Z,11Z,14Z)-N-(2-chloroethyl)icosa-5,8,11,14-tetraenamide; arachidonyl-2-chloroethylamide; N-(2-chloroethyl)-5Z,8Z,11Z,14Z-eicosatetraenamide

Appearance: Colorless Liquid

Formulation: A solution in methyl acetate

CAS Number: 220556-69-4

Structure Available?: TRUE

Peptide sequence:

Salt Form: FALSE

Molecular Formula: C₂₂H₃₆ClNO

Molecular Weight: 366

Cell-Permeable?: TRUE

Purity: ≥95%

Solubilities: ~30 mg/ml in DMF, ~20 mg/ml in DMSO, ~25 mg/ml in Ethanol

Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.

Country of Origin: USA

Tag Line: A high affinity agonist of cannabinoid receptor CB1

MDL Number: MFCD02683581

PubChem CID: 5311006

SMILES: CCCCCC=CCC=CCC=CCC=CCCCC(=O)NCCCl

InChi: InChI=1S/C22H36ClNO/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-22(25)24-21-20-23/h6-7,9-10,12-13,15-16H,2-5,8,11,14,17-21H2,1H3,(H,24,25)/b7-6-,10-9-,13-12-,16-15-

InChi Key: SCJNCDSAIRBRIA-DOFZRALJSA-