26
Arachidonoyl 2'-Chloroethylamide | B3015
- SKU:
- 26-B3015-GEN
- Availability:
- Usually shipped in 5 working days
Description
Arachidonyl-2-chloroethylamide (ACEA) is a high affinity agonist of cannabinoid receptor CB1. It binds to the CB1 receptor with high affinity (Ki value of 1.4 nM) and to the CB2 receptor with low affinity (Ki value of 3.1 μM). It inhibits forskolin-induced accumulation of cAMP in Chinese hamster ovary cells expressing the human CB1 receptor. It increases the binding of [35S]GTPgammaS to cerebellar membranes and inhibits electrically evoked contractions of the mouse vas deferens. It produces hypothermia in mice.
Arachidonyl-2-chloroethylamide (ACEA) is a high affinity agonist of cannabinoid receptor CB1. It binds to the CB1 receptor with high affinity (Ki value of 1.4 nM) and to the CB2 receptor with low affinity (Ki value of 3.1 μM). It inhibits forskolin-induced accumulation of cAMP in Chinese hamster ovary cells expressing the human CB1 receptor. It increases the binding of [35S]GTPgammaS to cerebellar membranes and inhibits electrically evoked contractions of the mouse vas deferens. It produces hypothermia in mice.
B3015 | Arachidonoyl 2'-Chloroethylamide DataSheet
Alternate Name/Synonyms: ACEA; (5Z,8Z,11Z,14Z)-N-(2-chloroethyl)icosa-5,8,11,14-tetraenamide; arachidonyl-2-chloroethylamide; N-(2-chloroethyl)-5Z,8Z,11Z,14Z-eicosatetraenamide
Appearance: Colorless Liquid
Formulation: A solution in methyl acetate
CAS Number: 220556-69-4
Structure Available?: TRUE
Peptide sequence:
Salt Form: FALSE
Molecular Formula: C₂₂H₃₆ClNO
Molecular Weight: 366
Cell-Permeable?: TRUE
Purity: ≥95%
Solubilities: ~30 mg/ml in DMF, ~20 mg/ml in DMSO, ~25 mg/ml in Ethanol
Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Country of Origin: USA
Tag Line: A high affinity agonist of cannabinoid receptor CB1
MDL Number: MFCD02683581
PubChem CID: 5311006
SMILES: CCCCCC=CCC=CCC=CCC=CCCCC(=O)NCCCl
InChi: InChI=1S/C22H36ClNO/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-22(25)24-21-20-23/h6-7,9-10,12-13,15-16H,2-5,8,11,14,17-21H2,1H3,(H,24,25)/b7-6-,10-9-,13-12-,16-15-
InChi Key: SCJNCDSAIRBRIA-DOFZRALJSA-
Additional Information
Storage Condition: |
-80ºC |
Shipping Condition: |
Dry Ice |
Shelf Life: |
36 months |