BW
ARHGDIG polyclonal Antibody | BS5899
- SKU:
- BW-BS5899
- Availability:
- Usually ships in 5 working days
Description
ARHGDIG polyclonal Antibody | BS5899 | Gentaur UK, US & Europe Distribution
Host: Rabbit
Reactivity: Human,Mouse
Application: WB ICC
Application Range: WB: 1:500~1:1000 ICC: 1:50~1:200
Background: The Ras superfamily of small GTP-binding proteins are critical mediators of diverse cell signaling pathways, including those leading to proliferation, cytoskeletal organization and secretion. The counter-conversion of the active GTPbound form of these proteins to their inactive GDP-bound form is influenced by two types of regulatory proteins: those that alter the intrinsic GTPase activity of the GTP-binding proteins and those that alter the rate of GDP/GTP exchange. Guanine nucleotide-releasing factors (GRFs) increase the GDP dissociation rate, while GDP-dissociation inhibitors (GDIs) decrease the dissociation rate. The Rho GDI subfamily is composed of Rho GDIα, Ly-GDI (also known as Rho GDIβ and previously known as GDI/D4) and Rho GDIγ. The Rho GDI proteins interact with and have varying affinities for several Ras-like GTP binding proteins, including Rho A, Rho B, Rac and Cdc42. Ly-GDI is expressed only in hematopoietic cells, predominantly in B and T lymphocyte cell lines.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: ARHGDIG polyclonal Antibody detects endogenous levels of ARHGDIG protein.
Molecular Weight: ~ 25 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: Rho GDP-dissociation inhibitor 3; Rho GDI 3; Rho-GDI gamma; Rho GDIγ; Rho-GDIγ
Immunogen: Synthetic peptide, corresponding to amino acids 176-221 of Human ARHGDIG.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Pathway: