ARHGEF7 Polyclonal Antibody | E-AB-14609

ARHGEF7 Polyclonal Antibody | E-AB-14609 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: ARHG7, ARHG7, ARHGEF 7, Arhgef7, Beta pix, Beta-Pix, betaPix, betaPix-b, betaPix-c, Cool, COOL-1, COOL1, DKFZp686C12170, DKFZp761K1021, KIAA0142, KIAA0412, mKIAA0142, Nbla10314, P50, P50BP, p85, P85COOL1, P85SPR, PAK interacting exchange factor beta, PAK-interacting exchange factor beta, PAK3, Pak3bp, PIX, PIXB, Rho guanine nucleotide exchange factor (GEF) 7, Rho guanine nucleotide exchange factor (GEF) 7b, Rho guanine nucleotide exchange factor (GEF7), Rho guanine nucleotide exchange factor 7, SH3 domain containing proline rich protein

Application: WB, IHC, ELISA

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer, Signal Transduction

Background: Rho GTPases play a fundamental role in numerous cellular processes triggered by extracellular stimuli that work through G protein coupled receptors. The encoded protein belongs to a family of cytoplasmic proteins that activate the Ras-like family of Rho proteins by exchanging bound GDP for GTP. It forms a complex with the small GTP binding protein Rac1 and recruits Rac1 to membrane ruffles and to focal adhesions. This protein can induce membrane ruffling. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Concentration: 0.2 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Recombinant protein of human ARHGEF7

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000, IHC 1:50-1:200

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 90 kDa

Molecular Weight(Observed): N/A