ARRY-797 | B2462

ARRY-797 is a potent and selective p38 mitogen-activated protein kinase inhibitor. Inhibits LPS-Induced IL-6 and In Vivo Growth of RPMI-8226 Human Multiple Myeloma Cells.

ARRY-797 is a potent and selective p38 mitogen-activated protein kinase inhibitor. Inhibits LPS-Induced IL-6 and In Vivo Growth of RPMI-8226 Human Multiple Myeloma Cells.

B2462 | ARRY-797 DataSheet

Alternate Name/Synonyms: 5-(2,4-difluorophenoxy)-N-(2-(dimethylamino)ethyl)-1-isobutyl-1H -indazole-6-carboxamide; ARRY797; ARRY-371797

Appearance: Crystalline solid

Formulation:

CAS Number: 1036404-17-7

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₂H₂₆F₂N₄O₂

Molecular Weight: 416.47

Cell-Permeable?: True

Purity: ≥98%

Solubilities: in DMSO

Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.

Country of Origin: USA

Tag Line: A potent and selective p38α inhibitor

MDL Number:

PubChem CID: N/A

SMILES: O=C(C1=CC2=C(C=C1OC3=CC=C(F)C=C3F)C=NN2CC(C)C)NCCN(C)C

InChi: InChI=1S/C22H26F2N4O2/c1-14(2)13-28-19-11-17(22(29)25-7-8-27(3)4)21(9-15(19)12-26-28)30-20-6-5-16(23)10-18(20)24/h5-6,9-12,14H,7-8,13H2,1-4H3,(H,25,29)

InChi Key: IFGWYHGYNVGVRB-UHFFFAOYSA-N