Description
ARRY-797 is a potent and selective p38 mitogen-activated protein kinase inhibitor. Inhibits LPS-Induced IL-6 and In Vivo Growth of RPMI-8226 Human Multiple Myeloma Cells.
ARRY-797 is a potent and selective p38 mitogen-activated protein kinase inhibitor. Inhibits LPS-Induced IL-6 and In Vivo Growth of RPMI-8226 Human Multiple Myeloma Cells.
Alternate Name/Synonyms: 5-(2,4-difluorophenoxy)-N-(2-(dimethylamino)ethyl)-1-isobutyl-1H -indazole-6-carboxamide; ARRY797; ARRY-371797
Appearance: Crystalline solid
Formulation:
CAS Number: 1036404-17-7
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₂₂H₂₆F₂N₄O₂
Molecular Weight: 416.47
Cell-Permeable?: True
Purity: ≥98%
Solubilities: in DMSO
Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Country of Origin: USA
Tag Line: A potent and selective p38α inhibitor
MDL Number:
PubChem CID: N/A
SMILES: O=C(C1=CC2=C(C=C1OC3=CC=C(F)C=C3F)C=NN2CC(C)C)NCCN(C)C
InChi: InChI=1S/C22H26F2N4O2/c1-14(2)13-28-19-11-17(22(29)25-7-8-27(3)4)21(9-15(19)12-26-28)30-20-6-5-16(23)10-18(20)24/h5-6,9-12,14H,7-8,13H2,1-4H3,(H,25,29)
InChi Key: IFGWYHGYNVGVRB-UHFFFAOYSA-N
Additional Information
Storage Condition: |
-20ºC |
Shipping Condition: |
Gel Pack |
Shelf Life: |
36 months |