26
AS-2444697 Hydrochloride | B1585
- SKU:
- 26-B1585-GEN
- Availability:
- Usually shipped in 5 working days
Description
AS-2444697 is a potent and selective interleukin-1 receptor-associated kinase 4 (IRAK4) inhibitor (IC₅₀ = 21 nM). It exhibits 30-fold selectivity for IRAK4 over IRAK1. Inhibits LPS-induced TNF-α and IL-6 production in PBMCs in vitro.
AS-2444697 is a potent and selective interleukin-1 receptor-associated kinase 4 (IRAK4) inhibitor (IC₅₀ = 21 nM). It exhibits 30-fold selectivity for IRAK4 over IRAK1. Inhibits LPS-induced TNF-α and IL-6 production in PBMCs in vitro.
B1585 | AS-2444697 Hydrochloride DataSheet
Alternate Name/Synonyms: N-(3-carbamoyl-1-(tetrahydro-2H-pyran-4-yl)-1H-pyrazol-4-yl)-2-(2-methylpyridin-4-yl)oxazole-4-carboxamide hydrochloride; AS-2444697
Appearance: Crystalline solid
Formulation: N/A
CAS Number: 1287665-60-4
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: N/A
Molecular Formula: C₉H₂₁ClN₆O₄
Molecular Weight: 432.86
Cell-Permeable?: yes
Purity: ≥98% by HPLC
Solubilities: DMSO
Handling: Protect from air and light
Country of Origin: USA
Tag Line: A potent and selective interleukin-1 receptor-associated kinase 4 (IRAK4) inhibitor
MDL Number: N/A
PubChem CID: N/A
SMILES: Cl.Cc1nccc(c1)c2occ(n2)C(=O)Nc3cn(nc3C(N)=O)C4CCOCC4
InChi: InChI=1S/C19H20N6O4.ClH/c1-11-8-12(2-5-21-11)19-23-15(10-29-19)18(27)22-14-9-25(24-16(14)17(20)26)13-3-6-28-7-4-13;/h2,5,8-10,13H,3-4,6-7H2,1H3,(H2,20,26)(H,22,27);1H
InChi Key: N/A
Additional Information
Storage Condition: |
-20°C |
Shipping Condition: |
Gel Pack |
Shelf Life: |
36 months |