Description
ASNA1 Antibody | 19-144 | Gentaur UK, US & Europe Distribution
Host: Rabbit
Reactivity: Human, Mouse, Rat
Homology: N/A
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-348 of human ASNA1 (NP_004308.2) .
Research Area: Cancer, Cell Cycle, Signal Transduction
Tested Application: WB, IHC
Application: WB: 1:200 - 1:2000
IHC: 1:50 - 1:200
Specificiy: N/A
Positive Control 1: U-251MG
Positive Control 2: MCF7
Positive Control 3: 293T
Positive Control 4: Mouse kidney
Positive Control 5: Mouse testis
Positive Control 6: Mouse brain
Molecular Weight: Observed: 39kDa
Validation: N/A
Isoform: N/A
Purification: Affinity purification
Clonality: Polyclonal
Clone: N/A
Isotype: IgG
Conjugate: Unconjugated
Physical State: Liquid
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration: N/A
Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.
Alternate Name: ASNA1, arsA arsenite transporter, ATP-binding, homolog 1 (bacterial) , ARSA-I, ARSA1, MGC3821, homolog 1, ARSA, TRC40
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: This gene represents the human homolog of the bacterial arsA gene, encoding the arsenite-stimulated ATPase component of the arsenite transporter responsible for resistance to arsenicals. This protein is also a central component of a transmembrane domain (TMD) recognition complex (TRC) that is involved in the post-translational delivery of tail-anchored (TA) proteins from the cytosol to the endoplasmic reticulum (ER) . It recognizes and selectively binds the TMD of TA proteins in the cytosol, and delivers them to the ER for insertion.