763

ASNA1 Polyclonal Antibody | E-AB-53162

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SKU:
763-E-AB-53162-GEN
£486.00 - £1,186.00

Description

ASNA1 Polyclonal Antibody | E-AB-53162 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: ARSA 1, ARSA, ArsA arsenite transporter ATP binding homolog 1, ArsA arsenite transporter, ATP binding, E. coli, homolog of, 1, ArsA arsenite transporter, ATP-binding, homolog 1 (bacterial), ARSA I, ARSA-I, ARSA1, ARSAI, Arsenical pump driving ATPase, Arsenical pump-driving ATPase, Arsenical resistance ATPase, Arsenite translocating ATPase, Arsenite transporting ATPase, Arsenite-stimulated ATPase, ASNA 1, ASNA I, ASNA-I, ASNA, ASNA1, Asna1 protein, ASNAI, ATPase ASNA1, GET3, Golgi to ER traffic 3 homolog, hARSA-I, hASNA-I, MGC3821, Transmembrane domain recognition complex 40 kDa ATPase subunit, Transmembrane domain recognition complex, 40kDa, TRC40

Application: IHC, ELISA

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer, Cell Biology, Metabolism, Signal Transduction

Background: ASNA1 (also known as TRC40) is a highly conserved ATPase involved in efflux of arsenite and antimonite. Reduced ASNA1 expression is associated with significant inhibition of cell growth, increased apoptosis and increased sensitivity to cisplatin and arsenite.Thus ASNA1 is proposed to be a target to overcome resistance to cancer chemotherapy. In addition, ASNA1 has been identified as an ER targeting factor for tail-anchored proteins in the posttranslational membrane insertion pathway.

Concentration: 1.26 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Fusion protein of human ASNA1

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification Method: Antigen affinity purification

Dilution: IHC 1:50-1:200, ELISA 1:5000-1:10000

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): N/A

Molecular Weight(Observed): N/A

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