ASY1 | Asynaptic phenotype protein 1 (monoclonal) | AS08 338

ASY1 | Asynaptic phenotype protein 1 (monoclonal) | AS08 338 | Gentaur UK, US & Europe Distribution

Immunogen: KLH-conjugated synthetic pepitde chosen from Triticum aestivum ASY1 UniProt: A7TVU8

Host: Mouse

Conjugation: N/A

Clonality: Monoclonal

Isotype: N/A

Purity: Total IgG. Protein G purified purified from Cell culture supernatant.

Format: Lyophilized

Tested Application: ELISA (ELISA), Western blot (WB)

Related Products: antibodies to proteins involved in DNA/RNA/Cell cycle

Recommended Dilutions: 1: 10 000 (ELISA), 1: 1000 (WB)

Molecular weight: 66, 3 kDa

Confirmed Reactivity: Triticum aestivum

Predicted Reactivity: Triticum aestivum

Not reactive in: No confirmed exceptions from predicted reactivity are currently known

Additional Information: This antibody does not work in immunolocalization

Background: Pairing and synapsis of homologous chromosomes is required for normal chromosome segregation and the exchange of genetic material via recombination during meiosis. Synapsis is complete at pachytene following the formation of a tri-partite proteinaceous structure known as the synaptonemal complex (SC) . In yeast, HOP1 is essential for formation of the SC, and localises along chromosome axes during prophase I. Homologues in Arabidopsis (AtASY1), Brassica (BoASY1) and rice (OsPAIR2) have been isolated through analysis of mutants that display decreased fertility due to severely reduced synapsis of homologous chromosomes. Analysis of these genes has indicated that they play a similar role to HOP1 in pairing and formation of the SC through localisation to axial/lateral elements of the SC.

Reconstitution: For reconstitution add 50 µl of sterile water/tube

Storage: Store lyophilized/reconstituted at -20°C; once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube.

TAIR Nnumbre: N/A

Category: Cell cycle

Research Area: Cell Biology