ASyM-biotinylated | Mouse anti-human alpha synuclein N-terminal | AS13 2719B

ASyM-biotinylated | Mouse anti-human alpha synuclein N-terminal | AS13 2719B | Gentaur UK, US & Europe Distribution

Immunogen: synthetic peptide derived from human alpha-synuclein N-terminal Met1-Val15

Host: Mouse

Conjugation: N/A

Clonality: Monoclonal

Isotype: IgG2a

Purity: Immunoglobulin affinity purified in PBS pH 7.4.

Format: Lyophilized

Tested Application: ELISA (ELISA)

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Recommended Dilutions: 2-4 ug/ml (ELISA capture)

Molecular weight: 14 kDa

Confirmed Reactivity: Human

Predicted Reactivity: N/A

Not reactive in: No confirmed exceptions from predicted reactivity are currently known

Additional Information: N/A

Background: Alpha-synuclein is normally an unstructured soluble protein that can aggregate to form insoluble fibrils in pathological conditions characterized by Lewy bodies, such as Parkinson's disease, dementia with Lewy-bodies, and multiple system atrophy. In analogy to many other amyloid associated disorders, alpha-synuclein may also form oligomeric assemblies. These small and soluble forms have been suggested to exert a stronger tissue damaging effect as compared to the monomeric and fibrillar counterpart. Using a recently developed technique a monoclonal oligomer-specific antibody has been designed.

Reconstitution: For reconstitution add 50 µl of sterile water

Storage: For short time storage add sodium azide and store at +4°C. For long time storage store lyophilized/reconstituted at -20°C; once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube.

TAIR Nnumbre: N/A

Category: Parkinson's disease

Research Area: Pathology, Amyloid Disorders