ATF6B (S425) polyclonal Antibody | BS2131

ATF6B (S425) polyclonal Antibody | BS2131 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: WB

Application Range: WB: 1:500~1:1000

Background: ATF-6 is a member of the basic-leucine zipper family of transcription factors. Endoplasmic reticulum stress causes cleavage of transmembrane ATF-6 and transclocation of active ATF-6 to the nucleus. Soluble ATF-6 can exist as either an ATF-6β homodimer or an ATF-6α/β heterodimer. Binding of the ATF-6β homodimer or ATF-6α/β heterodimer to the nuclear transcription factor Y C (NF-YC) induces ER chaperone transcription.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: ATF6B (S425) polyclonal Antibody detects endogenous levels of ATF6B protein.

Molecular Weight: ~ 90 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Cyclic AMP-dependent transcription factor ATF-6 beta; cAMP-dependent transcription factor ATF-6 beta; Activating transcription factor 6 beta; ATF6-beta; Protein G13; cAMP response element-binding protein-related protein; Creb-rp; cAMP-responsive element-binding protein-like 1; Processed cyclic AMP-dependent transcription factor ATF-6 beta; ATF6B; CREBL1; G13; ATF-6β; ATF6β

Immunogen: Synthetic peptide, corresponding to amino acids 390-442 of Human ATF6B.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: Vesicle Trafficking presynaptic signaling,