Atglistatin | B1864

Atglistatin is a potent, and selective inhibitor of adipose triglyceride lipase (ATGL) the rate limiting enzyme involved in fatty acid mobilization and prevention of lipolysis. It does not inhibit hormone-sensitive lipase, monoglyceride lipase, pancreatic lipase, lipoprotein lipase, or other lysophospholipases. Atglistatin also prevents triglyceride accumulation after acute myocardial infarction, displaying cardioprotective benefit.

Atglistatin is a potent, and selective inhibitor of adipose triglyceride lipase (ATGL) the rate limiting enzyme involved in fatty acid mobilization and prevention of lipolysis. It does not inhibit hormone-sensitive lipase, monoglyceride lipase, pancreatic lipase, lipoprotein lipase, or other lysophospholipases. Atglistatin also prevents triglyceride accumulation after acute myocardial infarction, displaying cardioprotective benefit.

B1864 | Atglistatin DataSheet

Alternate Name/Synonyms: 3-[3-[4-(dimethylamino)phenyl]phenyl]-1,1-dimethylurea

Appearance: White to of-white solid

Formulation: N/A

CAS Number: 1469924-27-3

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: N/A

Molecular Formula: C₁₇H₂₁N₃O

Molecular Weight: 283.37

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO (>15 mg/ml)

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A potent and selective adipose triglyceride lipase (ATGL) inhibitor

MDL Number: N/A

PubChem CID: 71699712

SMILES: CN(C)C1=CC=C(C=C1)C2=CC(=CC=C2)NC(=O)N(C)C

InChi: InChI=1S/C17H21N3O/c1-19(2)16-10-8-13(9-11-16)14-6-5-7-15(12-14)18-17(21)20(3)4/h5-12H,1-4H3,(H,18,21)

InChi Key: AWOPBSAJHCUSAS-UHFFFAOYSA-N