ATRIP Antibody | 22-734

ATRIP Antibody | 22-734 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse

Homology: N/A

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human ATRIP (NP_569055.1) .

Research Area: Other

Tested Application: WB, IP

Application: WB: 1:500 - 1:2000
IP: 1:50 - 1:200

Specificiy: N/A

Positive Control 1: HepG2

Positive Control 2: Jurkat

Positive Control 3: HeLa

Positive Control 4: Mouse brain

Positive Control 5: Mouse heart

Positive Control 6: N/A

Molecular Weight: Observed: 86kDa

Validation: N/A

Isoform: N/A

Purification: Affinity purification

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Concentration: N/A

Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.

Alternate Name: ATR-interacting protein, ATM and Rad3-related-interacting protein

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: This gene encodes an essential component of the DNA damage checkpoint. The encoded protein binds to single-stranded DNA coated with replication protein A. The protein also interacts with the ataxia telangiectasia and Rad3 related protein kinase, resulting in its accumulation at intranuclear foci induced by DNA damage. Multiple transcript variants encoding different isoforms have been found for this gene.