Description
ATRIP Antibody | 22-734 | Gentaur UK, US & Europe Distribution
Host: Rabbit
Reactivity: Human, Mouse
Homology: N/A
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human ATRIP (NP_569055.1) .
Research Area: Other
Tested Application: WB, IP
Application: WB: 1:500 - 1:2000
IP: 1:50 - 1:200
Specificiy: N/A
Positive Control 1: HepG2
Positive Control 2: Jurkat
Positive Control 3: HeLa
Positive Control 4: Mouse brain
Positive Control 5: Mouse heart
Positive Control 6: N/A
Molecular Weight: Observed: 86kDa
Validation: N/A
Isoform: N/A
Purification: Affinity purification
Clonality: Polyclonal
Clone: N/A
Isotype: IgG
Conjugate: Unconjugated
Physical State: Liquid
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration: N/A
Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.
Alternate Name: ATR-interacting protein, ATM and Rad3-related-interacting protein
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: This gene encodes an essential component of the DNA damage checkpoint. The encoded protein binds to single-stranded DNA coated with replication protein A. The protein also interacts with the ataxia telangiectasia and Rad3 related protein kinase, resulting in its accumulation at intranuclear foci induced by DNA damage. Multiple transcript variants encoding different isoforms have been found for this gene.