Description
AUDA | B3371
Description: AUDA is an inhibitor of soluble epoxide hydrolase (sEH) (displaying IC50 values of 18 and 69 nM for the mouse and human enzymes, respectively. Produces a hypotensive effect in angiotensin-infused rats and prevents and reverses cardiac hypertrophy in mouse models of cardiac hypertrophy. AUDA activates peroxisome proliferator-activated receptor α (PPARα) 3-fold at a concentration of 10 µM but exhibits no effect on PPARδ or PPARγ.
Alternate Name/Synonyms: 12-[[(tricyclo[3.3.1.13,7]dec-1-ylamino)carbonyl]amino]-dodecanoic acid
Appearance: Solid
Formulation:
CAS Number: 479413-70-2
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₂₃H₄₀N₂O₃
Molecular Weight: 392.6
Cell-Permeable?: True
Purity: ≥98%
Solubilities: ~1 mg/ml DMSO
Handling: Do not tr gloves and mask when handling the product! Avoid contact by all modes of exposure.
Tag Line: A soluble epoxide hydrolase (sEH) inhibitor
MDL Number:
PubChem CID: 10069117
PubChem CID Link: https://pubchem.ncbi.nlm.nih.gov/compound/10069117
SMILES: C1C2CC3CC1CC(C2)(C3)NC(=O)NCCCCCCCCCCCC(=O)O
InChi: InChI=1S/C23H40N2O3/c26-21(27)10-8-6-4-2-1-3-5-7-9-11-24-22(28)25-23-15-18-12-19(16-23)14-20(13-18)17-23/h18-20H,1-17H2,(H,26,27)(H2,24,25,28)
InChi Key: XLGSEOAVLVTJDH-UHFFFAOYSA-N
Category: Biochemicals
Additional Information
Storage Conditions: |
-20ºC |
Shipping Conditions: |
Gel Pack |
Shelf life: |
36 month |