AURKA (N-terminus) monoclonal Antibody | MB0116

AURKA (N-terminus) monoclonal Antibody | MB0116 | Gentaur UK, US & Europe Distribution

Host: Mouse

Reactivity: Human,Monkey

Application: WB

Application Range: WB:1:200~1000

Background: Aurora A plays a role in cell cycle regulation during anaphase and/or telophase, in relation to the function of the centrosome/spindle pole region during chromosome segregation. Aurora A plays a key role during tumor development and progression and is overexpressed in many human cancers including breast, ovarian and colorectal. Aurora A is viewed as a potential target for anticancer drug treatment.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: AURKA (N-terminus) mAb detects endogenous levels of AURKA protein.

Molecular Weight: Predicted band size:46KDa Observed band size:46KDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Aurora kinase A; Aurora 2; Aurora/IPL1-related kinase 1; ARK-1; Aurora-related kinase 1; hARK1; Breast tumor-amplified kinase; Serine/threonine-protein kinase 15; Serine/threonine-protein kinase 6; Serine/threonine-protein kinase aurora-A; AURKA; AIK; AIRK1; ARK1; AURA; AYK1; BTAK; IAK1; STK15; STK6

Immunogen: Recombinant full length Human AURKA (N-terminus) .

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: MAPK Erk in Growth and Differentiation Pathway,