Description
Azathioprine is a purine analog that displays immunosuppressive and anti-inflammatory properties. It serves as a prodrug for 6-mercaptopurine, which alters purine processing and DNA synthesis, interfering with the proliferation of lymphocytes and other myeloid cells.
Azathioprine is a purine analog that displays immunosuppressive and anti-inflammatory properties. It serves as a prodrug for 6-mercaptopurine, which alters purine processing and DNA synthesis, interfering with the proliferation of lymphocytes and other myeloid cells.
Alternate Name/Synonyms: 6-[(1-Methyl-4-nitro-1H-imidazol-5-yl)thio]-9H-purine
Appearance: Yellow solid
Formulation: N/A
CAS Number: 446-86-6
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₉H₇N₇O₂S
Molecular Weight: 277.26
Cell-Permeable?: Yes
Purity: ≥98% by HPLC
Solubilities: DMSO (>25 mg/ml)
Handling: Protect from air and light
Country of Origin: USA
Tag Line: An immunosuppressant
MDL Number: MFCD00069203
PubChem CID: 2265
SMILES: CN1C=NC(=C1SC2=NC=NC3=C2NC=N3)[N+](=O)[O-]
InChi: ChI=1S/C9H7N7O2S/c1-15-4-14-7(16(17)18)9(15)19-8-5-6(11-2-10-5)12-3-13-8/h2-4H,1H3,(H,10,11,12,13)
InChi Key: LMEKQMALGUDUQG-UHFFFAOYSA-N
Additional Information
Storage Condition: |
-20°C |
Shipping Condition: |
Gel Pack |
Shelf Life: |
36 months |