AZD-3463 | 2371

AZD-3463 is a potent ALK (Anaplastic Lymphoma Kinase)/IGFR1 dual inhibitor that displays ability to overcome acquired resistance to Crizotinib (Cat. No.1934).

AZD-3463 is a potent ALK (Anaplastic Lymphoma Kinase)/IGFR1 dual inhibitor that displays ability to overcome acquired resistance to Crizotinib (Cat. No.1934).

2371 | AZD-3463 DataSheet

Alternate Name/Synonyms: 2-Pyrimidinamine, N-[4-(4-amino-1-piperidinyl)-2-methoxyphenyl]-5-chloro-4-(1H-indol-3-yl

Appearance: Crystalline solid

Formulation: N/A

CAS Number: 1356962-20-3

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₄H₂₅ClN₆O

Molecular Weight: 448.95

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO (~20 mg/ml)

Handling: Protect from light and moisture

Country of Origin: USA

Tag Line: A potent ALK (Anaplastic Lymphoma Kinase)/IGFR1 dual inhibitor

MDL Number: N/A

PubChem CID: 56599293

SMILES: COC1=C(C=CC(=C1)N2CCC(CC2)N)NC3=NC=C(C(=N3)C4=CNC5=CC=CC=C54)Cl

InChi: InChI=1S/C24H25ClN6O/c1-32-22-12-16(31-10-8-15(26)9-11-31)6-7-21(22)29-24-28-14-19(25)23(30-24)18-13-27-20-5-3-2-4-17(18)20/h2-7,12-15,27H,8-11,26H2,1H3,(H,28,29,30)

InChi Key: GCYIGMXOIWJGBU-UHFFFAOYSA-N